Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis

Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis

Objective: We aimed at validating a plasma biomarker for neuronal damage that can be used in acute and chronic models of neurological diseases. Methods: We investigated two different models, middle cerebral artery occlusion followed by reperfusion and MOG35–55-induced experimental autoimmune encepha...

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Bibliographic Details
Main Authors: Mathias Gelderblom, Tristan Daehn, Benjamin Schattling, Peter Ludewig, Christian Bernreuther, Priyadharshini Arunachalam, Jakob Matschke, Markus Glatzel, Christian Gerloff, Manuel A. Friese, Tim Magnus
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Neurobiology of Disease
Subjects:
Stroke
Plasma biomarker
Neuronal damage
Neurological disease
Middle cerebral artery occlusion
MOG35–55-induced experimental autoimmune encephalomyelitis (EAE)
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002180

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http://www.sciencedirect.com/science/article/pii/S0969996113002180

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