Circulating LPS and (1→3)-β-D-Glucan: A Folie à Deux Contributing to HIV-Associated Immune Activation

Circulating LPS and (1→3)-β-D-Glucan: A Folie à Deux Contributing to HIV-Associated Immune Activation

Immune activation is the driving force behind the occurrence of AIDS and non-AIDS events, and is only partially reduced by antiretroviral therapy (ART). Soon after HIV infection, intestinal CD4+ T cells are depleted leading to epithelial gut damage and subsequent translocation of microbes and/or the...

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Bibliographic Details
Main Authors: Rayoun Ramendra, Stéphane Isnard, Vikram Mehraj, Jun Chen, Yonglong Zhang, Malcolm Finkelman, Jean-Pierre Routy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
HIV
LPS
(1→3)-β-D-Glucan
immune activation
microbial translocation
antiretroviral therapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00465/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00465/full

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