Serotonin-mediated tuning of human helper T cell responsiveness to the chemokine CXCL12.

In addition to its role as neurotransmitter, serotonin (5-HT) is an important modulator of inflammation and immunity. Here, we report novel findings suggesting a 5-HT involvement in T cell migration. In particular, we show that 5-HT tunes the responsiveness of human T lymphocytes to the broadly expr...

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Bibliographic Details
Main Authors: Elena Magrini, Ildikò Szabò, Andrea Doni, Javier Cibella, Antonella Viola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21853036/?tool=EBI