Functional and pharmacological characteristics of permeability transition in isolated human heart mitochondria.

The objective of the present study was to validate the presence and explore the characteristics of mitochondrial permeability transition (mPT) in isolated mitochondria from human heart tissue in order to investigate if previous findings in animal models of cardiac disorders are translatable to human...

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Bibliographic Details
Main Authors: Saori Morota, Theodor Manolopoulos, Atli Eyjolfsson, Per-Ola Kimblad, Per Wierup, Carsten Metzsch, Sten Blomquist, Magnus J Hansson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695980?pdf=render