Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs

Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs

Integrase strand transfer inhibitors (INSTIs) are currently recommended for the first line treatment of human immunodeficiency virus type one (HIV-1) infection. The first-generation INSTIs are effective but can select for resistant viruses. Recent advances have led to several potent second-generatio...

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Bibliographic Details
Main Authors: Steven J. Smith, Xue Zhi Zhao, Dario Oliveira Passos, Dmitry Lyumkis, Terrence R. Burke, Stephen H. Hughes
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
HIV
integration
INSTIs
drug resistance
antiviral therapy
Online Access:https://www.mdpi.com/1999-4915/13/2/205

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https://www.mdpi.com/1999-4915/13/2/205

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