Dopamine receptors reveal an essential role of IFT-B, KIF17, and Rab23 in delivering specific receptors to primary cilia

Appropriate physiological signaling by primary cilia depends on the specific targeting of particular receptors to the ciliary membrane, but how this occurs remains poorly understood. In this study, we show that D1-type dopaminergic receptors are delivered to cilia from the extra-ciliary plasma membr...

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Bibliographic Details
Main Authors: Alison Leaf, Mark Von Zastrow
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06996