Clusterin silencing restores myoblasts viability and down modulates the inflammatory process in osteoporotic disease

Clusterin silencing restores myoblasts viability and down modulates the inflammatory process in osteoporotic disease

Abstract Background Targeting new molecular pathways leading to Osteoporosis (OP) and Osteoarthritis (OA) is a hot topic for drug discovery. Clusterin (CLU) is a glycoprotein involved in inflammation, proliferation, cell death, neoplastic disease, Alzheimer disease and aging. The present study focus...

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Bibliographic Details
Main Authors: S. Pucci, C. Greggi, C. Polidoro, M. C. Piro, M. Celi, M. Feola, E. Gasbarra, R. Iundusi, F. Mastrangeli, G. Novelli, A. Orlandi, U. Tarantino
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Clusterin (CLU)
Osteoporosis
Osteoarthritis
Sarcopenia
Muscle waist
Osteoporosis marker
Online Access:http://link.springer.com/article/10.1186/s12967-019-1868-5

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http://link.springer.com/article/10.1186/s12967-019-1868-5

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