Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study

Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study

This study aimed to investigate the interactions between fingolimod, a sphingosine 1-phosphate receptor (S1PR) agonist, and melanocortin receptors 1 and 5 (MCR1, MCR5). In particular, we investigated the effects of fingolimod, a drug approved to treat relapsing-remitting multiple sclerosis, on retin...

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Bibliographic Details
Main Authors: Carlo Gesualdo, Cornel Balta, Chiara Bianca Maria Platania, Maria Consiglia Trotta, Hildegard Herman, Sami Gharbia, Marcel Rosu, Francesco Petrillo, Salvatore Giunta, Alberto Della Corte, Paolo Grieco, Rosa Bellavita, Francesca Simonelli, Michele D’Amico, Anca Hermenean, Settimio Rossi, Claudio Bucolo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
fingolimod
sphingosine 1-phosphate receptor
melanocortin receptor 1
melanocortin receptor 5
diabetic retinopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.718902/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.718902/full

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