Serum sdLDL-C and cellular SREBP2-dependent cholesterol levels: Is there a challenge on targeting PCSK9?

Background: Serum small dense LDL-cholesterol (sdLDLC) value is suggested to be an important risk factor for atherosclerosis. Since sdLDL-C changes may be related to PCSK9 and SREBP-2 functions, the aim of this study was to investigate correlations between sdLDL-C, circulating PCSK9, SREBP-2 express...

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Bibliographic Details
Main Authors: Soltanmohammadi Elham, Piran Sadegh, Mohammadi Asghar, Hosseni Bita, Naseri Faezeh, Shabani Mohammad, Najafi Mohammad
Format: Article
Language:English
Published: Society of Medical Biochemists of Serbia, Belgrade 2016-01-01
Series:Journal of Medical Biochemistry
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2016/1452-82581604410S.pdf