Carbamazepine Attenuates Astroglial L-Glutamate Release Induced by Pro-Inflammatory Cytokines via Chronically Activation of Adenosine A<sub>2A</sub> Receptor

Carbamazepine Attenuates Astroglial L-Glutamate Release Induced by Pro-Inflammatory Cytokines via Chronically Activation of Adenosine A<sub>2A</sub> Receptor

Carbamazepine (CBZ) binds adenosine receptors, but detailed effects of CBZ on astroglial transmission associated with adenosine receptor still need to be clarified. To clarify adenosinergic action of CBZ on astroglial transmission, primary cultured astrocytes were acutely or chronically treated with...

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Bibliographic Details
Main Authors: Motohiro Okada, Kouji Fukuyama, Takashi Shiroyama, Yuto Ueda
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
carbamazepine
L-glutamate
adenosine receptor
tripartite synaptic transmission
astrocyte
Online Access:https://www.mdpi.com/1422-0067/20/15/3727

Internet

https://www.mdpi.com/1422-0067/20/15/3727

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