Transcriptome profiling of the diaphragm in a controlled mechanical ventilation model reveals key genes involved in ventilator-induced diaphragmatic dysfunction

Transcriptome profiling of the diaphragm in a controlled mechanical ventilation model reveals key genes involved in ventilator-induced diaphragmatic dysfunction

Abstract Background Ventilator-induced diaphragmatic dysfunction (VIDD) is associated with weaning difficulties, intensive care unit hospitalization (ICU), infant mortality, and poor long-term clinical outcomes. The expression patterns of long noncoding RNAs (lncRNAs) and mRNAs in the diaphragm in a...

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Bibliographic Details
Main Authors: Ruining Liu, Gang Li, Haoli Ma, Xianlong Zhou, Pengcheng Wang, Yan Zhao
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Genomics
Subjects:
Controlled mechanical ventilation
Ventilator-induced Diaphragmatic dysfunction
RNA-seq
lncRNA
mRNA
Online Access:https://doi.org/10.1186/s12864-021-07741-9

Internet

https://doi.org/10.1186/s12864-021-07741-9

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