Propylthiouracil is teratogenic in murine embryos.

Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD) propylthiouracil (PTU) and methimazole (MMI). PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects have not been...

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Bibliographic Details
Main Authors: Valeria C Benavides, Murali K Mallela, Carmen J Booth, Christopher C Wendler, Scott A Rivkees
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329451?pdf=render