Antidepressant Potential of Chlorogenic Acid-Enriched Extract from Eucommia ulmoides Oliver Bark with Neuron Protection and Promotion of Serotonin Release through Enhancing Synapsin I Expression

Antidepressant Potential of Chlorogenic Acid-Enriched Extract from Eucommia ulmoides Oliver Bark with Neuron Protection and Promotion of Serotonin Release through Enhancing Synapsin I Expression

Eucommia ulmoides Oliver (E. ulmoides) is a traditional Chinese medicine with many beneficial effects, used as a tonic medicine in China and other countries. Chlorogenic acid (CGA) is an important compound in E. ulmoides with neuroprotective, cognition improvement and other pharmacological effects....

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Bibliographic Details
Main Authors: Jianming Wu, Haixia Chen, Hua Li, Yong Tang, Le Yang, Shousong Cao, Dalian Qin
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
chlorogenic acid
Eucommia ulmoides Oliver
cerebrospinal fluid
UHPLC-ESI-MS/MS
antidepressant
raphe neurons
serotonin
synapsin I
Online Access:http://www.mdpi.com/1420-3049/21/3/260

Internet

http://www.mdpi.com/1420-3049/21/3/260

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