The Bone Marrow Microenvironment as Niche Retreats for Hematopoietic and Leukemic Stem Cells
Leukemia poses a serious challenge to current therapeutic strategies. This has been attributed to leukemia stem cells (LSCs), which occupy endosteal and sinusoidal niches in the bone marrow similar to those of hematopoietic stem cells (HSCs). The signals from these niches provide a viable setting fo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2013-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2013/953982 |