Knockdown of lncRNA PVT1 alleviates high glucose-induced proliferation and fibrosis in human mesangial cells by miR-23b-3p/WT1 axis

Knockdown of lncRNA PVT1 alleviates high glucose-induced proliferation and fibrosis in human mesangial cells by miR-23b-3p/WT1 axis

Abstract Background Diabetic nephropathy (DN) is a severe complication of diabetes with type 1 and 2. Long non-coding RNAs (lncRNAs) are being found to be involved in the DN pathogenesis. In this study, we aimed to further explore the effect and underlying mechanism of plasmacytoma variant transloca...

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Bibliographic Details
Main Authors: Wen Zhong, Jiaoe Zeng, Junli Xue, Aimin Du, Yancheng Xu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Diabetology & Metabolic Syndrome
Subjects:
DN
PVT1
miR-23b-3p
WT1
High glucose
Online Access:http://link.springer.com/article/10.1186/s13098-020-00539-x

Internet

http://link.springer.com/article/10.1186/s13098-020-00539-x

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