Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance

Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance

Increases in plasma LDL-cholesterol have unequivocally been established as a causal risk factor for atherosclerosis. Hence, strategies for lowering of LDL-cholesterol may have immediate therapeutic relevance. Here we study the role of human neutrophil peptide 1 (HNP1) in a mouse model of atheroscler...

Full description

Bibliographic Details
Main Authors: Nicole Paulin, Yvonne Döring, Sander Kooijman, Xavier Blanchet, Joana R. Viola, Renske de Jong, Manuela Mandl, Jeffrey Hendrikse, Maximilian Schiener, Philipp von Hundelshausen, Anja Vogt, Christian Weber, Khalil Bdeir, Susanna M. Hofmann, Patrick C.N. Rensen, Maik Drechsler, Oliver Soehnlein
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:EBioMedicine
Subjects:
Neutrophil
Human neutrophil peptide
LDL receptor
Atherosclerosis
Hypercholesterolemia
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417300063

Internet

http://www.sciencedirect.com/science/article/pii/S2352396417300063

Similar Items