Epigenetics and microRNAs in UGT1As

Abstract UDP-glucuronosyltransferases (UGTs) are the main phase II drug-metabolizing enzymes mediating the most extensive glucuronidation-binding reaction in the human body. The UGT1A family is involved in more than half of glucuronidation reactions. However, significant differences exist in the dis...

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Bibliographic Details
Main Authors: Cui-Lan Meng, Wei Zhao, Dan-Ni Zhong
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-021-00331-6