Decentralizing Cell-Free RNA Sensing With the Use of Low-Cost Cell Extracts

Decentralizing Cell-Free RNA Sensing With the Use of Low-Cost Cell Extracts

Cell-free gene expression systems have emerged as a promising platform for field-deployed biosensing and diagnostics. When combined with programmable toehold switch-based RNA sensors, these systems can be used to detect arbitrary RNAs and freeze-dried for room temperature transport to the point-of-n...

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Bibliographic Details
Main Authors: Anibal Arce, Fernando Guzman Chavez, Chiara Gandini, Juan Puig, Tamara Matute, Jim Haseloff, Neil Dalchau, Jenny Molloy, Keith Pardee, Fernán Federici
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cell-free
toehold-sensor
low-cost
diagnostics
decentralization
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.727584/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.727584/full

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