Water without windows: Evaluating the performance of open cell transmission electron microscopy under saturated water vapor conditions, and assessing its potential for microscopy of hydrated biological specimens.

We have performed open cell transmission electron microscopy experiments through pure water vapor in the saturation pressure regime (>0.6 kPa), in a modern microscope capable of sub-Å resolution. We have systematically studied achievable pressure levels, stability and gas purity, effective thickn...

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Bibliographic Details
Main Authors: Cathal Cassidy, Masao Yamashita, Martin Cheung, Chola Kalale, Hidehito Adaniya, Ryusuke Kuwahara, Tsumoru Shintake
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5669482?pdf=render