Contributions of Noncanonical Smoothened Signaling During Embryonic Development
The Sonic Hedgehog (Shh) signaling pathway is active during embryonic development in metazoans, and provides instructional cues necessary for proper tissue patterning. The pathway signal transducing component, Smoothened (Smo), is a G protein-coupled receptor (GPCR) that has been demonstrated to sig...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-10-01
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Series: | Journal of Developmental Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2221-3759/5/4/11 |