Contributions of Noncanonical Smoothened Signaling During Embryonic Development

The Sonic Hedgehog (Shh) signaling pathway is active during embryonic development in metazoans, and provides instructional cues necessary for proper tissue patterning. The pathway signal transducing component, Smoothened (Smo), is a G protein-coupled receptor (GPCR) that has been demonstrated to sig...

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Bibliographic Details
Main Authors: Tanushree Pandit, Stacey K. Ogden
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Journal of Developmental Biology
Subjects:
Online Access:https://www.mdpi.com/2221-3759/5/4/11