A comparison of estimators from self-controlled case series, case-crossover design, and sequence symmetry analysis for pharmacoepidemiological studies

A comparison of estimators from self-controlled case series, case-crossover design, and sequence symmetry analysis for pharmacoepidemiological studies

Abstract Background Despite the frequent use of self-controlled methods in pharmacoepidemiological studies, the factors that may bias the estimates from these methods have not been adequately compared in real-world settings. Here, we comparatively examined the impact of a time-varying confounder and...

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Bibliographic Details
Main Authors: Yoshinori Takeuchi, Tomohiro Shinozaki, Yutaka Matsuyama
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Medical Research Methodology
Subjects:
Bias
Interaction
Medical database
Misspecified risk period
Restriction
Self-controlled methods
Online Access:http://link.springer.com/article/10.1186/s12874-017-0457-7

Internet

http://link.springer.com/article/10.1186/s12874-017-0457-7

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