Preparation of Temozolomide-Loaded Nanoparticles for Glioblastoma Multiforme Targeting—Ideal Versus Reality

Temozolomide (TMZ) is one of the most effective chemotherapeutic agents for glioblastoma multiforme, but the required high administration dose is accompanied by side effects. To overcome this problem and to further improve TMZ’s efficacy, targeted delivery of TMZ by using polymeric nanoparticles has...

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Bibliographic Details
Main Authors: Chooi Yeng Lee, Ing Hong Ooi
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/9/3/54