Improved clinical outcomes of high risk β thalassemia major patients undergoing a HLA matched related allogeneic stem cell transplant with a treosulfan based conditioning regimen and peripheral blood stem cell grafts.

Improved clinical outcomes of high risk β thalassemia major patients undergoing a HLA matched related allogeneic stem cell transplant with a treosulfan based conditioning regimen and peripheral blood stem cell grafts.

Improving clinical outcomes among high risk Class III β thalassemia major patients (Class IIIHR) receiving an allogeneic SCT remains a challenge. From October, 2009 a treosulfan based regimen (TreoFluT) was used for all consecutive Class III patients (n = 50). The clinical outcomes were compared wit...

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Bibliographic Details
Main Authors: Vikram Mathews, Biju George, Auro Viswabandya, Aby Abraham, Rayaz Ahmed, Abhijeet Ganapule, Eunice Sindhuvi, Kavitha M Lakshmi, Alok Srivastava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637210?pdf=render

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http://europepmc.org/articles/PMC3637210?pdf=render

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