Enhanced gene silencing through human serum albumin-mediated delivery of polyethylenimine-siRNA polyplexes.

Small interfering RNA (siRNA) targeted therapeutics (STT) offers a compelling alternative to tradition medications for treatment of genetic diseases by providing a means to silence the expression of specific aberrant proteins, through interference at the expression level. The perceived advantage of...

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Bibliographic Details
Main Authors: Elena Nicolì, Marie Isabel Syga, Michela Bosetti, V Prasad Shastri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391875?pdf=render