Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2

Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative virus of the coronavirus disease 2019 (COVID-19) pandemic. To establish a safe and convenient assay system for studying entry inhibitors and neutralizing antibodies against SARS-CoV-2, we constructed a codon-optimized, ful...

Full description

Bibliographic Details
Main Authors: Jie Hu, Qingzhu Gao, Changlong He, Ailong Huang, Ni Tang, Kai Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Genes and Diseases
Subjects:
Antiviral therapeutics
Coronavirus
Neutralizing antibodies
Pseudovirus
SARS-CoV-2
Spike protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300891

Internet

http://www.sciencedirect.com/science/article/pii/S2352304220300891

Similar Items