Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells

Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells

Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury (AKI). However, the potential function of MSCs in chronic kidney disease remains elusive. Renal fibrosis is the common endpoint of chronic progressive kidney diseases and causes a considerable health burden worldwide....

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Bibliographic Details
Main Authors: Lei Wu, Chao Rong, Qing Zhou, Xin Zhao, Xue-Mei Zhuansun, Shan Wan, Mao-Min Sun, Shou-Li Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
bone marrow mesenchymal stem cells
renal fibrosis
microRNA
TGF-β1
renal tubular epithelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.623693/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.623693/full

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