The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection.

The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection.

The main features of lung infection and inflammation are a massive recruitment of neutrophils and the subsequent release of neutrophil serine proteases (NSPs). Anti-infectious and/or anti-inflammatory treatments must be tested on a suitable animal model. Mice models do not replicate several aspects...

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Bibliographic Details
Main Authors: Claire Chevaleyre, Mickaël Riou, Déborah Bréa, Clarisse Vandebrouck, Céline Barc, Jérémy Pezant, Sandrine Melo, Michel Olivier, Rémy Delaunay, Olivier Boulesteix, Patricia Berthon, Christelle Rossignol, Julien Burlaud Gaillard, Frédéric Becq, Francis Gauthier, Mustapha Si-Tahar, François Meurens, Mustapha Berri, Ignacio Caballero-Posadas, Sylvie Attucci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5161375?pdf=render

Internet

http://europepmc.org/articles/PMC5161375?pdf=render

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