Lactobacillus plantarum Strains Can Enhance Human Mucosal and Systemic Immunity and Prevent Non-steroidal Anti-inflammatory Drug Induced Reduction in T Regulatory Cells

Lactobacillus plantarum Strains Can Enhance Human Mucosal and Systemic Immunity and Prevent Non-steroidal Anti-inflammatory Drug Induced Reduction in T Regulatory Cells

Orally ingested bacteria interact with intestinal mucosa and may impact immunity. However, insights in mechanisms involved are limited. In this randomized placebo-controlled cross-over trial, healthy human subjects were given Lactobacillus plantarum supplementation (strain TIFN101, CIP104448, or WCF...

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Bibliographic Details
Main Authors: Paul de Vos, Zlatan Mujagic, Bart J. de Haan, Roland J. Siezen, Peter A. Bron, Marjolein Meijerink, Jerry M. Wells, Ad A. M. Masclee, Mark V. Boekschoten, Marijke M. Faas, Freddy J. Troost
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
intestinal mucosal immunity
adaptive immunity
Lactobacillus plantarum
indomethacin
non-steroidal anti-inflammatory drug
probiotics
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01000/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01000/full

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