Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection.

We present immunological data from two clinical trials where the effect of experimental human hookworm (Necator americanus) infection on the pathology of celiac disease was evaluated. We found that basal production of Interferon- (IFN-)γ and Interleukin- (IL-)17A from duodenal biopsy culture was sup...

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Bibliographic Details
Main Authors: Henry J McSorley, Soraya Gaze, James Daveson, Dianne Jones, Robert P Anderson, Andrew Clouston, Nathalie E Ruyssers, Richard Speare, James S McCarthy, Christian R Engwerda, John Croese, Alex Loukas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3174943?pdf=render