Prospective study of epigenetic alterations responsible for isolated hemihyperplasia/hemihypoplasia and their association with leg length discrepancy

Prospective study of epigenetic alterations responsible for isolated hemihyperplasia/hemihypoplasia and their association with leg length discrepancy

Abstract Background Hemihyperplasia and hemihypoplasia result in leg length discrepancy (LLD) by causing skeletal asymmetry. Beckwith–Wiedemann syndrome (BWS) and Silver–Russell syndrome (SRS) are opposite growth-affecting disorders caused by opposite epigenetic alterations at the same chromosomal l...

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Bibliographic Details
Main Authors: Chang Ho Shin, Chaemoon Lim, Hwa Young Kim, Won Joon Yoo, Tae-Joon Cho, In Ho Choi, Jung Min Ko
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Hemihyperplasia
Hemihypoplasia
Lateralized overgrowth
Beckwith–Wiedemann syndrome
Silver–Russell syndrome
Leg length discrepancy
Online Access:https://doi.org/10.1186/s13023-021-02042-6

Internet

https://doi.org/10.1186/s13023-021-02042-6

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