HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. The aim of this investigation was to determine the e...

Full description

Bibliographic Details
Main Authors: Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
Mitochondria
Stress response
Obesity
Glucose homeostasis
Insulin resistance
Adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001216

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821001216

Similar Items