Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis

Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis

Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease. The potential role of xenobiotic metabolizing enzymes, such as the glutathione transferases (GSTs), in...

Full description

Bibliographic Details
Main Authors: Zorica Reljic, Mario Zlatovic, Ana Savic-Radojevic, Tatjana Pekmezovic, Ljubica Djukanovic, Marija Matic, Marija Pljesa-Ercegovac, Jasmina Mimic-Oka, Dejan Opsenica, Tatjana Simic
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Toxins
Subjects:
Balkan endemic nephropathy
biotransformation
glutathione transferase A1
ochratoxin A
polymorphism
Online Access:http://www.mdpi.com/2072-6651/6/8/2348

Internet

http://www.mdpi.com/2072-6651/6/8/2348

Similar Items