Genome Maintenance Proteins Modulate Autoimmunity Mediated Primed Adaptation by the <i>Escherichia coli</i> Type I-E CRISPR-Cas System

Genome Maintenance Proteins Modulate Autoimmunity Mediated Primed Adaptation by the <i>Escherichia coli</i> Type I-E CRISPR-Cas System

Bacteria and archaea use CRISPR-Cas adaptive immunity systems to interfere with viruses, plasmids, and other mobile genetic elements. During the process of adaptation, CRISPR-Cas systems acquire immunity by incorporating short fragments of invaders&#8217; genomes into CRISPR arrays. The acquisit...

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Bibliographic Details
Main Authors: Elena Kurilovich, Anna Shiriaeva, Anastasia Metlitskaya, Natalia Morozova, Ivana Ivancic-Bace, Konstantin Severinov, Ekaterina Savitskaya
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Genes
Subjects:
crispr-cas
<i>escherichia coli</i>
primed adaptation
dna repair
Online Access:https://www.mdpi.com/2073-4425/10/11/872

Internet

https://www.mdpi.com/2073-4425/10/11/872

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