Calreticulin expression in human cardiac myocytes induces ER stress‐associated apoptosis

Abstract The global burden of heart failure following myocardial ischemia‐reperfusion (IR) injury is a growing problem. One pathway that is key to understanding the progression of myocardial infarction and IR injury is the endoplasmic reticulum (ER) stress pathway, which contributes to apoptosis sig...

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Bibliographic Details
Main Authors: Michael W. Stoner, Charles F. McTiernan, Iain Scott, Janet R. Manning
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14400