The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect

The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect

Abstract Background Endothelial progenitor cells (EPCs) are non-differentiated endothelial cells (ECs) present in blood circulation that are involved in neo-vascularization and correction of damaged endothelial sites. Since EPCs from patients with vascular disorders are impaired and inefficient, all...

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Bibliographic Details
Main Authors: Sina Naserian, Mohamed Essameldin Abdelgawad, Mazdak Afshar Bakshloo, Guillaume Ha, Nassim Arouche, José L. Cohen, Benoît L. Salomon, Georges Uzan
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cell Communication and Signaling
Subjects:
Endothelial Progenitor Cells (EPCs)
Endothelial Colony Forming Cells (ECFCs)
T cells
Immune regulation
Immune-checkpoint
TNFα/TNFR2 signaling pathway
Online Access:http://link.springer.com/article/10.1186/s12964-020-00564-3

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http://link.springer.com/article/10.1186/s12964-020-00564-3

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