The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy

The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy

Abstract Wnt signaling was initially recognized to be vital for tissue development and homeostasis maintenance. Further studies revealed that this pathway is also important for tumorigenesis and progression. Abnormal expression of signaling components through gene mutation or epigenetic regulation i...

Full description

Bibliographic Details
Main Authors: Zhuo Wang, Tingting Zhao, Shihui Zhang, Junkai Wang, Yunyun Chen, Hongzhou Zhao, Yaxin Yang, Songlin Shi, Qiang Chen, Kuancan Liu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Biomarker Research
Subjects:
Wnt signaling
beta-catenin
Epigenetic modification
Tumor microenvironment
Drug development
Online Access:https://doi.org/10.1186/s40364-021-00323-7

Internet

https://doi.org/10.1186/s40364-021-00323-7

Similar Items