Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein.

Many viruses alter expression of proteins on the surface of infected cells including molecules important for immune recognition, such as the major histocompatibility complex (MHC) class I and II molecules. Virus-induced downregulation of surface proteins has been observed to occur by a variety of me...

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Bibliographic Details
Main Authors: Joseph R Francica, Angel Varela-Rohena, Andrew Medvec, Gabriela Plesa, James L Riley, Paul Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2936550?pdf=render