Investigating Patterns of Immune Interaction in Ovarian Cancer: Probing the O-glycoproteome by the Macrophage Galactose-Like C-type Lectin (MGL)

Investigating Patterns of Immune Interaction in Ovarian Cancer: Probing the O-glycoproteome by the Macrophage Galactose-Like C-type Lectin (MGL)

Glycosylation, the posttranslational linking of sugar molecules to proteins, is notoriously altered during tumor transformation. More specifically in carcinomas, GalNAc-type <i>O</i>-glycosylation, is characterized by biosynthetically immature truncated glycans present on the cancer cell...

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Bibliographic Details
Main Authors: Chiara Napoletano, Catharina Steentoff, Federico Battisti, Zilu Ye, Hassan Rahimi, Ilaria Grazia Zizzari, Marco Dionisi, Bruna Cerbelli, Federica Tomao, Deborah French, Giulia d’Amati, Pierluigi Benedetti Panici, Sergey Vakhrushev, Henrik Clausen, Marianna Nuti, Aurelia Rughetti
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
Epithelial ovarian cancer
MGL/CLEC10A/CD301
<i>O</i>-glycosylation
Tn antigen
cancer immunotherapy
DCs
Online Access:https://www.mdpi.com/2072-6694/12/10/2841

Internet

https://www.mdpi.com/2072-6694/12/10/2841

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