Tau Phosphorylation by GSK3 in Different Conditions

Almost a 20% of the residues of tau protein are phosphorylatable amino acids: serine, threonine, and tyrosine. In this paper we comment on the consequences for tau of being a phosphoprotein. We will focus on serine/threonine phosphorylation. It will be discussed that, depending on the modified resid...

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Bibliographic Details
Main Authors: Jesús Avila, Gonzalo León-Espinosa, Esther García, Vega García-Escudero, Félix Hernández, Javier DeFelipe
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2012/578373