A PIANO (Proper, Insufficient, Aberrant, and NO Reprogramming) Response to the Yamanaka Factors in the Initial Stages of Human iPSC Reprogramming

A PIANO (Proper, Insufficient, Aberrant, and NO Reprogramming) Response to the Yamanaka Factors in the Initial Stages of Human iPSC Reprogramming

Yamanaka reprogramming is revolutionary but inefficient, slow, and stochastic. The underlying molecular events for these mixed outcomes of induction of pluripotent stem cells (iPSC) reprogramming is still unclear. Previous studies about transcriptional responses to reprogramming overlooked human rep...

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Bibliographic Details
Main Author: Kejin Hu
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
human induced pluripotent stem cells
human iPSC
reprogramming legitimacy
aberrant reprogramming
transcriptional profiling
reprogramome
Online Access:https://www.mdpi.com/1422-0067/21/9/3229

Internet

https://www.mdpi.com/1422-0067/21/9/3229

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