KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency

KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency

As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we systematically assessed cellular and molecular ha...

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Bibliographic Details
Main Authors: Shin-Il Kim, Fabian Oceguera-Yanez, Ryoko Hirohata, Sara Linker, Keisuke Okita, Yasuhiro Yamada, Takuya Yamamoto, Shinya Yamanaka, Knut Woltjen
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000600

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http://www.sciencedirect.com/science/article/pii/S2213671115000600

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