Jagged Ligands Enhance the Pro-Angiogenic Activity of Multiple Myeloma Cells

Jagged Ligands Enhance the Pro-Angiogenic Activity of Multiple Myeloma Cells

Multiple myeloma (MM) is an incurable plasma cell malignancy arising primarily within the bone marrow (BM). During MM progression, different modifications occur in the tumor cells and BM microenvironment, including the angiogenic shift characterized by the increased capability of endothelial cells t...

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Bibliographic Details
Main Authors: Maria Teresa Palano, Domenica Giannandrea, Natalia Platonova, Germano Gaudenzi, Monica Falleni, Delfina Tosi, Elena Lesma, Valentina Citro, Michela Colombo, Ilaria Saltarella, Roberto Ria, Nicola Amodio, Elisa Taiana, Antonino Neri, Giovanni Vitale, Raffaella Chiaramonte
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
multiple myeloma
angiogenesis
Notch
Jagged
VEGF
bone marrow stromal cells
Online Access:https://www.mdpi.com/2072-6694/12/9/2600

Internet

https://www.mdpi.com/2072-6694/12/9/2600

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