Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

Summary: Eosinophils mediate protection against filarial nematodes. Our results demonstrate that eosinophil extracellular traps (EETosis) are induced by microfilariae and infective L3 larvae of Litomosoides sigmodontis. These extracellular DNA traps inhibit microfilariae motility in a DNA- and conta...

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Bibliographic Details
Main Authors: Alexandra Ehrens, Benjamin Lenz, Anna-Lena Neumann, Samuela Giarrizzo, Julia Jennifer Reichwald, Stefan Julian Frohberger, Wiebke Stamminger, Benedikt Christian Buerfent, Frédéric Fercoq, Coralie Martin, Daniel Kulke, Achim Hoerauf, Marc Peter Hübner
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cell Reports
Subjects:
filaria
extracellular DNA traps
eosinophils
microfilaria
L3 larva
ETosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720316107

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http://www.sciencedirect.com/science/article/pii/S2211124720316107

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