Similarity analysis, synthesis, and bioassay of antibacterial cyclic peptidomimetics

Similarity analysis, synthesis, and bioassay of antibacterial cyclic peptidomimetics

The chemical similarity of antibacterial cyclic peptides and peptidomimetics was studied in order to identify new promising cyclic scaffolds. A large descriptor space coupled with cluster analysis was employed to digitize known antibacterial structures and to gauge the potential of new peptidomimeti...

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Bibliographic Details
Main Authors: Workalemahu M. Berhanu, Mohamed A. Ibrahim, Girinath G. Pillai, Alexander A. Oliferenko, Levan Khelashvili, Farukh Jabeen, Bushra Mirza, Farzana Latif Ansari, Ihsan ul-Haq, Said A. El-Feky, Alan R. Katritzky
Format: Article
Language:English
Published: Beilstein-Institut 2012-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antibacterial
cluster analysis
N-acylbenzotriazoles
peptidomimetics
similarity
Online Access:https://doi.org/10.3762/bjoc.8.128

Internet

https://doi.org/10.3762/bjoc.8.128

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