Presaging critical residues in protein interfaces-web server (PCRPi-W): a web server to chart hot spots in protein interfaces.

It is well established that only a portion of residues that mediate protein-protein interactions (PPIs), the so-called hot spot, contributes the most to the total binding energy, and thus its identification is an important and relevant question that has clear applications in drug discovery and prote...

Full description

Bibliographic Details
Main Authors: Joan Segura Mora, Salam A Assi, Narcis Fernandez-Fuentes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2925954?pdf=render