Cytosolic Replication of Group A Streptococcus in Human Macrophages

As key components of innate immune defense, macrophages are essential in controlling bacterial pathogens, including group A Streptococcus (GAS). Despite this, only a limited number of studies have analyzed the recovery of GAS from within human neutrophils and macrophages. Here, we determined the int...

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Bibliographic Details
Main Authors: Alan M. O’Neill, Teresa L. M. Thurston, David W. Holden
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e00020-16