Helicobacter pylori VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection
Helicobacter pylori has coexisted with humans for at least 60.000 years and has evolved persistence strategies that allow it to evade host immunity and colonize its host for life. The VacA protein is expressed by all H. pylori strains and is required for high-level persistent infection in experiment...
Main Authors: | Aleksandra Altobelli, Michael Bauer, Karelia Velez, Timothy L. Cover, Anne Müller |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-03-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.00261-19 |
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