Systemic Glycosaminoglycan Clearance by HARE/Stabilin-2 Activates Intracellular Signaling

Systemic Glycosaminoglycan Clearance by HARE/Stabilin-2 Activates Intracellular Signaling

Scavenger receptors perform essential functions, critical to maintaining mammalian physiologic homeostasis by continuously clearing vast numbers of biomolecules from blood, interstitial fluid and lymph. Stabilin-2 (Stab2) and the Hyaluronic Acid Receptor for Endocytosis (HARE), a proteolytic isoform...

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Bibliographic Details
Main Author: Paul H. Weigel
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
clathrin-coated pit
ERK1/2
phagocytosis
receptor isoform
receptor-mediated endocytosis
receptor recycling
Online Access:https://www.mdpi.com/2073-4409/9/11/2366

Internet

https://www.mdpi.com/2073-4409/9/11/2366

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