Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons

Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons

Abstract Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs), and, in turn, provide feedback inhibition onto PC dendrites. Excitatory synapses onto SOM-INs show a Hebbian long-term potentiat...

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Bibliographic Details
Main Authors: Anne-Sophie Racine, François-Xavier Michon, Isabel Laplante, Jean-Claude Lacaille
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Molecular Brain
Subjects:
GABA interneurons
Somatotropin-release inhibitory factor—SRIF
Whole cell recordings
Cysteamine
SST1-5 receptors
Disinhibition
Online Access:https://doi.org/10.1186/s13041-021-00830-6

Internet

https://doi.org/10.1186/s13041-021-00830-6

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