Single nucleotide polymorphisms in the 3'UTR of VPAC-1 cooperate in modulating gene expression and impact differently on the interaction with miR525-5p.

Complex immune and neurodegenerative disorders are the result of multiple interactions between common genetic variations having, individually, a weak effect on the disease susceptibility or resistance. Interestingly, some genes have been found to be associated with more than one disease although not...

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Bibliographic Details
Main Authors: Fabiana Paladini, Nicla Porciello, Giorgio Camilli, Sinem Tuncer, Elisa Cocco, Maria Teresa Fiorillo, Rosa Sorrentino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4229240?pdf=render